[Remote] Senior Director, Trade & Channel Operations

Note: The job is a remote job and is open to candidates in USA. Amylyx Pharmaceuticals is a clinical-stage company focused on treating diseases with high unmet needs. The Senior Director, Trade & Channel Operations will be responsible for building the U.S. distribution and channel model in preparation for a commercial launch, architecting the distribution strategy, and ensuring operational alignment across various functions.ResponsibilitiesDesign and build Amylyx’s U.S. distribution model across specialty pharmacy, specialty distributor, and 3PL channels to support product launchLead contracting strategy for specialty pharmacies and distributors, including negotiating distribution and service agreements, fee schedules, data requirements, and service levelsIntegrate distribution channels with service programs and field initiatives to enable a seamless customer experienceCollaborate with Supply Chain and Finance to support 3PL operations, including order‑to‑cash processes, inventory management, data exchange, shipping, returns, and chargeback managementEstablish and manage noncommercial and free‑goods pharmacy operationsForecast and model channel performance, assess specialty pharmacy throughput, and provide recommendations to ensure timely, reliable patient accessDevelop distribution analytics including inventory visibility, service metrics, dispense data, time to therapy, and partner scorecards; lead specialty pharmacy QBRsPartner cross‑functionally with Supply Chain, Quality, Compliance, Legal, Finance, Patient Services, and Commercial Operations to ensure operational alignment and launch readinessServe as a senior leader within Market Access, contributing to launch planning, forecasting, patient access workflows, and overall distribution strategyContinuously optimize post‑launch distribution operations by driving root‑cause remediation, vendor KPI management, and process improvements informed by field and service feedbackSkillsBachelor's degree required12+ years of experience in biopharmaceutical trade and distribution, including leadership of specialty pharmacy and distributor channel networksPrior product launch experience in the US marketExperience designing and implementing channel strategies for product launchesProven ability to assess, manage, and influence channel partner performance to contractual expectationsHands‑on experience with 3PL operations, serialization, state licensing, and compliant distribution processesDemonstrated strength in contract negotiation, vendor management, and commercial channel operationsDeep understanding of payer reimbursement, hub/patient support integration, channel economics, and order‑to‑cash workflowsProven leadership experience, including managing large pharmaceutical vendors, with demonstrated people management skillsExcellent communication, vendor management, analytical, and project execution capabilitiesCompany OverviewAmylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain. It was founded in 2014, and is headquartered in Cambridge, Massachusetts, USA, with a workforce of 51-200 employees. Its website is http://amylyx.com.