[Remote] Senior Product Manager, Clinical Genomics

Note: The job is a remote job and is open to candidates in USA. Natera is a global leader in cell-free DNA testing, focused on oncology, women’s health, and organ health. They are seeking a Senior Product Manager to define and drive strategy for the Results, Interpretation, and Reporting platform, ensuring cohesive and compliant clinical software systems that support complex genomics workflows across multiple business units.ResponsibilitiesDefine and drive multi-year product strategy and roadmap across one or more RIR components, ensuring alignment to clinical quality, regulatory requirements, and commercial scale objectivesInfluence platform-level technical direction in partnership with engineering leadershipPartner closely with software engineering, bioinformatics, clinical domain experts, quality, regulatory, and other product teamsTranslate business, clinical, and operational needs into clear, actionable product requirementsDefine and evolve end-to-end user workflows, including UI/UX requirements and supporting backend functionalityDrive cross-team alignment on shared data contracts and workflow standardsMentor and raise the bar for product management within the RIR organizationOwn measurable improvements in clinical workflow efficiency, reliability, and operational scalabilityEstablish prioritization frameworks that balance regulatory risk, clinical impact, technical scalability, and business outcomes across RIR investmentsDevelop and track quantitative metrics related to usability, performance, reliability, and adoptionLead delivery teams with clear strategic direction, ensuring requirements reflect long-term platform goals, validation readiness, and system interoperabilityProactively identify systemic risks, architectural constraints, and workflow inefficiencies that may limit scale or regulatory robustness, and lead cross-functional initiatives to resolve themPartner with Quality and Regulatory leadership to shape validation strategy, risk classification, traceability, and audit readiness for RIR software systemsCreate clear, data-driven written proposals and presentations to support stakeholder alignment and decision-makingAct as a subject matter expert for owned components, supporting design, testing, validation, rollout, and ongoing useSkillsBachelor's degree in life sciences, engineering, computer science, statistics, or equivalent experience5+ years of experience in software product management, including ownership of complex, multi-team or platform-level initiatives5+ years experience working on production software in healthcare, clinical genomics, or other regulated lifesciences domains, with demonstrated impact on validation, compliance, and system scalabilityDemonstrated experience influencing engineering architecture and long-term technical investment decisionsProven ability to drive alignment across highly matrixed organizations without direct authorityTrack record of independently operating in ambiguous environments and establishing product directionExperience with clinical genomics and variant processing and interpretation workflowsExperience owning user-facing applications, tools, or operational softwareFamiliarity working with backend services, APIs, or data-driven systemsBenefitsComprehensive medical, dental, vision, life and disability plans for eligible employees and their dependentsNatera employees and their immediate families receive free testingFertility care benefitsPregnancy and baby bonding leave401k benefitsCommuter benefitsGenerous employee referral programCompany OverviewNatera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health. It was founded in 2004, and is headquartered in San Carlos, California, USA, with a workforce of 5001-10000 employees. Its website is https://www.natera.com/.Company H1B SponsorshipNatera has a track record of offering H1B sponsorships, with 6 in 2026, 90 in 2025, 72 in 2024, 37 in 2023, 71 in 2022, 64 in 2021, 40 in 2020. Please note that this does not guarantee sponsorship for this specific role.