Senior Lead, Clinical Project Manager

Responsible for providing leadership, governance, industry expertise and best practices to our clients, client projects and the teams dedicated to serving them. Responsible for staff management and directing and managing services for client projects to assure high quality, on-time, and on-budget services while promoting excellent customer service.At Clario, a part of Thermo Fisher Scientific, we are committed to transforming clinical trials through innovation, expertise, and collaboration. As a Senior Lead Clinical Project Manager, Oncology, you will provide strategic and operational leadership across complex, high‑profile oncology studies, ensuring excellence in delivery, quality, and client partnership. This role blends hands‑on project leadership with people management, process improvement, and cross‑functional influence in a global environment.

What We Offer
Opportunity to lead complex, global oncology programs with high visibility

A collaborative, science‑driven environment focused on quality and innovation

Professional growth through leadership, mentoring, and therapeutic expertise

The ability to influence operational strategy and process improvement at scale


What You’ll Be Doing
Provide oversight of study management and overall project delivery, ensuring timelines, budgets, and quality standards are met

Evaluate and monitor study progress and project management workload; implement corrective actions as needed

Proactively identify, manage, and mitigate risks across a portfolio of studies

Lead escalation management to resolve internal and external study challenges effectively

Develop and apply structured problem‑solving strategies; maintain issue‑tracking documentation to ensure timely resolution

Support Clinical Project Managers in client communications related to study status, risks, and mitigation plans

Manage internal and external negotiations while fostering collaboration, clear communication, and efficient resource utilization

Assess feasibility and resourcing for global projects, partnering with applicable global teams

Independently lead Start‑Up, Execution, and Closeout phases for complex, non‑standard, high‑profile studies

Perform Project Manager duties as needed to support study success

Keep senior management informed of study status, risks, and resourcing needs

Guide study teams to ensure consistency across therapeutic programs, optimizing efficiencies and alignment with customer objectives

Identify opportunities to improve efficiency and quality through process, tools, and workflow enhancements

Own and drive therapeutic area initiatives and process improvements, including planning, execution, communication, and progress reporting.


What We Look For
Bachelor’s degree in life sciences, pharmacy, nursing, or equivalent; Master’s degree preferred

5–10 years of clinical trials experience within a CRO or pharmaceutical research organization, with a strong emphasis on project management

Prior experience managing or leading clinical development projects for investigational medications

Strong knowledge of the drug development process, GCP/ICH guidelines, and FDA regulations

Demonstrated ability to mentor, coach, and develop project management staff

Experience with oncology studies required; medical imaging experience is a plus

Excellent organizational, interpersonal, time management, and communication skills

Proven ability to manage multiple complex projects and competing priorities

Proficiency with Microsoft Office applications

Detail‑ and goal‑oriented mindset with a high level of responsiveness and professionalism

Valid passport and ability to travel approximately 20%

EEO Statement
Clario is an equal opportunity employer. Clario evaluates qualified applicants without regard to race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, protected veteran status, disability/handicap status, or any other legally protected characteristic.

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