[Remote] Senior Bioinformatics Scientist

Note: The job is a remote job and is open to candidates in USA. Natera is a global leader in cell-free DNA testing, dedicated to oncology, women’s health, and organ health. They are seeking a Senior Bioinformatics Scientist to lead the architecture, development, and automation of high-throughput genomic pipelines, focusing on building production-grade software tools for analyzing next-generation sequencing data.ResponsibilitiesAnalyze complex genomic datasets leveraging scaled in-house pipelines, partnering cross-functionally with wet-lab scientists and statisticians to rapidly deliver data-driven answers to critical research goalsArchitect, build, and deploy automated analysis pipelines for diagnostic tests, integrating robust capabilities for fusion detection, variant calling, and automated quality control metricsEngineer novel genomic analysis tools and proactively identify optimization pathways to enhance pipeline accuracy and efficiencyParticipate in code reviews, technical documentation, and the continuous improvement of core computational workflowsCoordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systemsSkillsPh.D. or Master's degree with a minimum of 5 years of professional experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative fieldDeep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflowsAdvanced understanding of data structures, algorithm design, and computational complexityStrong software engineering proficiency in Java or C++ within a professional production environmentDemonstrated scripting capability in Python or Perl for data manipulation, automation, and rapid prototypingDeep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scriptsDemonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challengesExcellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholdersPrior experience working with relational databases, particularly MySQL, is highly desirableBenefitsComprehensive medical, dental, vision, life and disability plans for eligible employees and their dependentsNatera employees and their immediate families receive free testing in addition to fertility care benefitsPregnancy and baby bonding leave401k benefitsCommuter benefitsGenerous employee referral programCompany OverviewNatera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health. It was founded in 2004, and is headquartered in San Carlos, California, USA, with a workforce of 5001-10000 employees. Its website is https://www.natera.com/.Company H1B SponsorshipNatera has a track record of offering H1B sponsorships, with 6 in 2026, 90 in 2025, 72 in 2024, 37 in 2023, 71 in 2022, 64 in 2021, 40 in 2020. Please note that this does not guarantee sponsorship for this specific role.