[Remote] Genomic Scientist

Note: The job is a remote job and is open to candidates in USA. Boston Children's Hospital is dedicated to supporting pediatric researchers with access to digital tools and technologies. As a Genomic Scientist, you will lead bioinformatic analyses of various sequencing data to enhance the diagnosis and treatment of pediatric rare diseases and contribute to advancing rare disease research.ResponsibilitiesProducing innovative solutions driven by exploratory data analysis of complex and high-dimensional datasets; applying knowledge of statistics, machine learning, programming, data modeling, and advanced mathematics to generate and test hypotheses and interpret the results of experimentsWith minimal supervision and direction, completing assignments in the required timeframe while consistently adhering to standard operating procedures and best practices; adapting to a changing environment, resolving problems associated with assignments, and seeking supervisor assistance when neededLeading Research Computing projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectivesTraining staff and researchers; effectively tailoring presentations; developing, implementing, and maintaining knowledge management systemsContributing to a range of communications (e.g. scientific presentations and publications) that clearly deliver content; preparing communications appropriate for management and internal distributionsPresenting at project and internal meetings; effectively conveying progress and asserting point of view; constructively discussing issues and providing facts; building credibility and trust by asking thoughtful questions and actively listening; running productive project meetings that advance problem-solvingSkillsBachelor's degree, PhD preferredA minimum of one year of position-specific experienceExtensive experience with next-generation sequencing, particularly exome and whole genome sequencing analysisStrong programming and bioinformatics skills. Proficiency with Bash, Python and/or R is requiredExperience working with high performance computing clustersAbility to critically evaluate medical and scientific literature with strong analytical and problem solving skillsStrong organizational skills with the ability to independently manage multiple tasks and projects in a fast-paced environmentExcellent written, verbal, and problem-solving skillsCollaborative team player with demonstrated initiative, independence, and attention to detailPreference for candidates with strong prior computational biology experience, potentially through completion of a PhD program and a strong publication recordFamiliarity with pipeline management tools such as Nextflow, WDL and Snakemake is desiredFamiliarity with clinical NGS testing and genomic data interpretation resources, including variant classification based on the ACMG guidelines, is preferredCompany OverviewBoston Children's Hospital is a 404-bed comprehensive center for pediatric health care. It was founded in 1869, and is headquartered in Sandwich, Massachusetts, USA, with a workforce of 10001+ employees. Its website is https://www.childrenshospital.org/.Company H1B SponsorshipBoston Children's Hospital has a track record of offering H1B sponsorships, with 3 in 2024, 3 in 2023, 2 in 2022, 4 in 2020. Please note that this does not guarantee sponsorship for this specific role.