[Remote] DMPK Consultant

Note: The job is a remote job and is open to candidates in USA. Edison Scientific builds and commercializes AI agents for science, aiming to accelerate scientific discovery through autonomous AI. They are seeking an experienced DMPK Specialist for a part-time consulting role to provide expertise on the scientific integrity of AI-generated DMPK outputs, influencing DMPK practices across the industry.ResponsibilitiesAdvise on the development of high-quality DMPK training data spanning the discovery-to-IND workflow — including in vitro ADME panels, in vivo PK across preclinical species, metabolite identification, NCA outputs, and PBPK/population PK simulationsProvide guidance on optimal data sources, including synthetic generation, consortia, licensed datasets, and public PK/ADME databasesReview and validate AI-generated DMPK outputs — PK parameter estimates, model fits, ADME interpretations, dose projections, and written report sections — for scientific accuracy and regulatory complianceCollaborate with our Engineering, Evals, and Science teams to benchmark agent performance against gold-standard DMPK workflowsProvide expert input to help refine agent logic, data quality, and overall platform capabilitiesSkills10+ years of hands-on DMPK experience supporting programs from discovery through IND, or direct ownership of 10+ IND-reaching programsProven ability to translate CRO bioanalytical data, in vitro ADME results, and in vivo PK study reports into FDA-ready IND DMPK submissionsStrong proficiency in PK modeling, with experience in at least one PBPK platform (Simcyp, GastroPlus, or PK-Sim)End-to-end ADME fluencyComfortable working independently as the primary DMPK voice in an advisory capacityEnthusiastic about working with AI/LLM tools to evaluate and improve scientific outputsExperience with regulatory DDI strategy, including PBPK-based DDI predictions submitted to FDA/EMAPK/PD modeling or quantitative systems pharmacology (QSP) experiencePrior AI/ML work applied to DMPK or ADME property predictionBackground at big pharma or CROs supporting large pharma IND programsCompany OverviewEdison Scientific accelerates scientific discovery using an AI research platform for autonomous R&D. It was founded in 2025, and is headquartered in San Francisco, California, USA, with a workforce of 51-200 employees. Its website is https://edisonscientific.com/.