Medical Monitoring Manager - Oncology
Translational Research in Oncology (TRIO) is a global clinical research organization dedicated to advancing cancer research in the clinical trial setting. Our passionate team is committed to bringing cancer treatments of the future to the world of today.
We are seeking an experienced physician leader to head our Medical Monitoring Unit, ensuring the medical and scientific integrity of oncology clinical trials across Phase I–III studies. This is a role that goes beyond individual study oversight, requiring the ability to manage people, complexity, and competing priorities within a dynamic and growing portfolio.
The ideal candidate brings deep oncology and medical monitoring expertise, combined with strong managerial capability, sound judgment, and the ability to navigate fast-moving, data-rich, and often ambiguous environments. They will balance scientific rigor with operational practicality, communicate effectively across stakeholders, and lead with a high level of ownership, credibility, and strategic perspective.
Reporting directly to the Vice President, Medical Affairs, this position offers a remote or hybrid work model, depending on the candidate’s location and preference.
Key Responsibilities
Lead, manage, and further develop the Medical Monitoring Unit, including direct oversight of multiple Medical Monitors
Ensure consistent, high-quality medical monitoring across oncology trials from Phase I through Phase III
Provide expert medical guidance on protocol interpretation, safety events, eligibility, and benefit-risk assessment
Act as a senior medical point of contact for sponsors, investigators, and internal stakeholders
Drive consistency, quality standards, and best practices across studies and across the team
Manage resource allocation and priorities across a complex and evolving study portfolio
Contribute to study and portfolio-level planning, including alignment with budgets and cross-functional collaboration
Support hiring, coaching, and retention of high-performing medical staff
Partner closely with cross-functional teams including Clinical Operations, Drug Safety, Medical Writing, and Regulatory
QualificationsMedical Doctor (MD) required; oncology specialization strongly preferred
8 –10+ years of experience in clinical research
Proven experience as a Medical Monitor in oncology clinical trials (Phase I–III)
Strong background in safety review and medical decision-making in active oncology studies
Demonstrated experience in people management and team leadership
Experience managing multiple studies or programs simultaneously
Strong understanding of clinical trial design and regulatory frameworks (ICH-GCP, FDA, EMA)
Fluent English required; Spanish is a plus
CRO experience strongly preferred; Pharma experience will also be considered
What TRIO Can Offer You
Opportunity to lead a critical function within an oncology-focused organization
High-impact role with visibility across senior leadership
Exposure to a diverse and scientifically meaningful oncology portfolio
A role combining medical depth, leadership responsibility, and strategic influence
Annual compensation review with opportunities for professional growth
3 weeks of vacation plus paid December Holiday Closure
10 days paid personal/sick time
1 paid volunteer day / year
A rich benefit plan with Health, Dental, Vision & Life Insurance premiums paid by TRIO
Up to 5% RRSP Matching Program
Voluntary TFSA Program Available
Flexible working hours to create work-life balance
Monthly Internet Allowance to support working from home and a one-time Home Office Allowance
Out-of-country Work: Employees can request to work internationally for a short period of time each year
Maternity / Parental Leave Top-Up Program
Employee Family Assistance Program to support you and your family during difficult times
Employee Recognition Program to reward long-term employees
Employee Referral Bonus Program
Pay Range: $150,000 to $200,000 CAD - Salary to be influenced (or determined) by the education, experience, location, knowledge, skills, abilities of the applicant, internal equity, and alignment with market data.
If you are interested, please submit your resume in English. We thank all candidates for their interest; only those selected for an interview will be contacted.
Prior to applying please review TRIO's Applicant Information Notice
To support efficiency, TRIO may use limited AI tools during the candidate review process. All hiring decisions are made by people, not AI.
To ensure fairness and an accurate understanding of your skills, we ask that candidates refrain from using AI tools or AI‑generated responses during interviews or assessments. We want the opportunity to get to know you and your experience.
Teamwork · Passion · Integrity · Innovation
We are seeking an experienced physician leader to head our Medical Monitoring Unit, ensuring the medical and scientific integrity of oncology clinical trials across Phase I–III studies. This is a role that goes beyond individual study oversight, requiring the ability to manage people, complexity, and competing priorities within a dynamic and growing portfolio.
The ideal candidate brings deep oncology and medical monitoring expertise, combined with strong managerial capability, sound judgment, and the ability to navigate fast-moving, data-rich, and often ambiguous environments. They will balance scientific rigor with operational practicality, communicate effectively across stakeholders, and lead with a high level of ownership, credibility, and strategic perspective.
Reporting directly to the Vice President, Medical Affairs, this position offers a remote or hybrid work model, depending on the candidate’s location and preference.
Key Responsibilities
Lead, manage, and further develop the Medical Monitoring Unit, including direct oversight of multiple Medical Monitors
Ensure consistent, high-quality medical monitoring across oncology trials from Phase I through Phase III
Provide expert medical guidance on protocol interpretation, safety events, eligibility, and benefit-risk assessment
Act as a senior medical point of contact for sponsors, investigators, and internal stakeholders
Drive consistency, quality standards, and best practices across studies and across the team
Manage resource allocation and priorities across a complex and evolving study portfolio
Contribute to study and portfolio-level planning, including alignment with budgets and cross-functional collaboration
Support hiring, coaching, and retention of high-performing medical staff
Partner closely with cross-functional teams including Clinical Operations, Drug Safety, Medical Writing, and Regulatory
QualificationsMedical Doctor (MD) required; oncology specialization strongly preferred
8 –10+ years of experience in clinical research
Proven experience as a Medical Monitor in oncology clinical trials (Phase I–III)
Strong background in safety review and medical decision-making in active oncology studies
Demonstrated experience in people management and team leadership
Experience managing multiple studies or programs simultaneously
Strong understanding of clinical trial design and regulatory frameworks (ICH-GCP, FDA, EMA)
Fluent English required; Spanish is a plus
CRO experience strongly preferred; Pharma experience will also be considered
What TRIO Can Offer You
Opportunity to lead a critical function within an oncology-focused organization
High-impact role with visibility across senior leadership
Exposure to a diverse and scientifically meaningful oncology portfolio
A role combining medical depth, leadership responsibility, and strategic influence
Annual compensation review with opportunities for professional growth
3 weeks of vacation plus paid December Holiday Closure
10 days paid personal/sick time
1 paid volunteer day / year
A rich benefit plan with Health, Dental, Vision & Life Insurance premiums paid by TRIO
Up to 5% RRSP Matching Program
Voluntary TFSA Program Available
Flexible working hours to create work-life balance
Monthly Internet Allowance to support working from home and a one-time Home Office Allowance
Out-of-country Work: Employees can request to work internationally for a short period of time each year
Maternity / Parental Leave Top-Up Program
Employee Family Assistance Program to support you and your family during difficult times
Employee Recognition Program to reward long-term employees
Employee Referral Bonus Program
Pay Range: $150,000 to $200,000 CAD - Salary to be influenced (or determined) by the education, experience, location, knowledge, skills, abilities of the applicant, internal equity, and alignment with market data.
If you are interested, please submit your resume in English. We thank all candidates for their interest; only those selected for an interview will be contacted.
Prior to applying please review TRIO's Applicant Information Notice
To support efficiency, TRIO may use limited AI tools during the candidate review process. All hiring decisions are made by people, not AI.
To ensure fairness and an accurate understanding of your skills, we ask that candidates refrain from using AI tools or AI‑generated responses during interviews or assessments. We want the opportunity to get to know you and your experience.
Teamwork · Passion · Integrity · Innovation