Global Imaging and Medical Physics Head
Global Imaging and Medical Physics Head
Position Summary
The Global Imaging and Medical Physics Head leads the imaging and dosimetry components of RLT clinical programs, ensuring accurate patient-specific planning and site qualifications. This specialized role integrates medical physics with clinical imaging to optimize therapeutic outcomes in radiopharmaceutical therapies. Reporting to the CMO or Head of Clinical Development, it focuses on clinical imaging, OLINDA modeling, dosimetry plans, and site readiness for RLT delivery.
Key Responsibilities
Clinical Imaging Ownership: Oversee the design and implementation of imaging protocols (e.g., PET/CT, SPECT) for RLT trials, ensuring standardization and data quality for biodistribution and response assessment.
OLINDA Modeling: Lead the use of OLINDA/EXM software for organ-level dosimetry modeling, predicting radiation doses from RLT agents to inform safe dosing.
Patient-Specific Dosimetry Planning: Develop and execute individualized dosimetry plans, integrating imaging data with pharmacokinetic models to personalize RLT treatments and minimize toxicity.
Site Qualification: Qualify and train clinical sites for RLT imaging and physics requirements, including equipment calibration, radiation safety, and data transfer protocols.
Data Analysis and Integration: Analyze imaging and dosimetry data to support clinical endpoints, safety monitoring, and regulatory submissions.
Innovation in Physics: Advance RLT methodologies, such as AI-enhanced dosimetry or novel imaging biomarkers.
Cross-Functional Collaboration: Partner with clinical operations, regulatory, and R&D to embed imaging/physics into trial designs.
Team Building: Lead a team of medical physicists and imaging specialists (including contractors and CROs).
Qualifications
• MD in Nuclear Medicine or PhD in medical physics, nuclear medicine, or related field; board certification (e.g., ABR) preferred.
• 8+ years in medical physics/imaging within biotech/pharma, with RLT experience.
• Proficiency in OLINDA, dosimetry software, and imaging modalities (PET/SPECT).
• Strong understanding of radiation biology and patient-specific modeling.
• Excellent problem-solving skills, with experience in site qualifications and regulatory compliance.
Compensation
Actithera offers a competitive compensation package designed to reward both performance and expertise through market-based, results-driven pay.
For this role, the anticipated base salary range is $250,000 – $350,000, complemented by eligibility for an annual bonus, equity participation, and a comprehensive benefits program.
Your actual salary will be determined based on the scope of the role and your unique experience and capabilities—because we know great contributions come from great people.
Actithera is proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability or any other status protected under federal, state or local law. All employment is decided on the basis of qualifications, merit and business need.
Location
Cambridge, Massachusetts (Remote)
Employment Type
Full-Time
Minimum Experience
Executive
Compensation
$250,000-$350,000
Position Summary
The Global Imaging and Medical Physics Head leads the imaging and dosimetry components of RLT clinical programs, ensuring accurate patient-specific planning and site qualifications. This specialized role integrates medical physics with clinical imaging to optimize therapeutic outcomes in radiopharmaceutical therapies. Reporting to the CMO or Head of Clinical Development, it focuses on clinical imaging, OLINDA modeling, dosimetry plans, and site readiness for RLT delivery.
Key Responsibilities
Clinical Imaging Ownership: Oversee the design and implementation of imaging protocols (e.g., PET/CT, SPECT) for RLT trials, ensuring standardization and data quality for biodistribution and response assessment.
OLINDA Modeling: Lead the use of OLINDA/EXM software for organ-level dosimetry modeling, predicting radiation doses from RLT agents to inform safe dosing.
Patient-Specific Dosimetry Planning: Develop and execute individualized dosimetry plans, integrating imaging data with pharmacokinetic models to personalize RLT treatments and minimize toxicity.
Site Qualification: Qualify and train clinical sites for RLT imaging and physics requirements, including equipment calibration, radiation safety, and data transfer protocols.
Data Analysis and Integration: Analyze imaging and dosimetry data to support clinical endpoints, safety monitoring, and regulatory submissions.
Innovation in Physics: Advance RLT methodologies, such as AI-enhanced dosimetry or novel imaging biomarkers.
Cross-Functional Collaboration: Partner with clinical operations, regulatory, and R&D to embed imaging/physics into trial designs.
Team Building: Lead a team of medical physicists and imaging specialists (including contractors and CROs).
Qualifications
• MD in Nuclear Medicine or PhD in medical physics, nuclear medicine, or related field; board certification (e.g., ABR) preferred.
• 8+ years in medical physics/imaging within biotech/pharma, with RLT experience.
• Proficiency in OLINDA, dosimetry software, and imaging modalities (PET/SPECT).
• Strong understanding of radiation biology and patient-specific modeling.
• Excellent problem-solving skills, with experience in site qualifications and regulatory compliance.
Compensation
Actithera offers a competitive compensation package designed to reward both performance and expertise through market-based, results-driven pay.
For this role, the anticipated base salary range is $250,000 – $350,000, complemented by eligibility for an annual bonus, equity participation, and a comprehensive benefits program.
Your actual salary will be determined based on the scope of the role and your unique experience and capabilities—because we know great contributions come from great people.
Actithera is proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability or any other status protected under federal, state or local law. All employment is decided on the basis of qualifications, merit and business need.
Location
Cambridge, Massachusetts (Remote)
Employment Type
Full-Time
Minimum Experience
Executive
Compensation
$250,000-$350,000